A coupling esterification reaction is conduced to produce lauryl alcohol sodium alginate modified sodium alginate and flake inorganic LDH nanoparticles with positively charged surface are used as emulsifiers in an aqueous dispersion system, solid particles and anionic polymeric surfactant are closely integrated to form a layer of dense oil / water interfacial film through electrostatic interaction, so as to prepare the stable sustained-release drug-loading Pickering emulsion. The invention relates to the technical field of drug controlled release, and in particular relates to a preparation method of a drug-loading Pickering emulsion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.) Filing date Publication date Application filed by Hainan University filed Critical Hainan University Priority to CN201510169051.1A priority Critical patent/CN104823970B/en Publication of CN104823970A publication Critical patent/CN104823970A/en Application granted granted Critical Publication of CN104823970B publication Critical patent/CN104823970B/en Status Active legal-status Critical Current Anticipated expiration legal-status Critical Links Original Assignee Hainan University Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.) ( en Inventor 李嘉诚 冯玉红 林强 刘若林 魏思宝 颜慧琼 Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.) Granted Application number CN201510169051.1A Other languages Chinese ( zh) Google Patents Preparation method of drug-loading Pickering emulsionĭownload PDF Info Publication number CN104823970A CN104823970A CN201510169051.1A CN201510169051A CN104823970A CN 104823970 A CN104823970 A CN 104823970A CN 201510169051 A CN201510169051 A CN 201510169051A CN 104823970 A CN104823970 A CN 104823970A Authority CN China Prior art keywords sodium alginate pickering emulsion preparation medicine carrying drug Prior art date Legal status (The legal status is an assumption and is not a legal conclusion. Google Patents CN104823970A - Preparation method of drug-loading Pickering emulsion CN104823970A - Preparation method of drug-loading Pickering emulsion
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